COVID during pregnancy

Up to one in five women will experience a miscarriage in their lifetime and 1% of women will suffer three or more miscarriages. There are large gaps of knowledge related to miscarriage which means that many women do not get an explanation as to why it happened or the ability to predict the chances of it happening again in the future.

Since 2016 researchers have been following women and collecting data throughout pregnancy to understand miscarriage better and find ways to predict the occurrence. Over 1,500 pregnant women have had a huge amount of information collected with 230 of these pregnancies sadly resulting in miscarriage.

As an additional focus, the research is also using the data from this study to find out more about whether COVID infection during pregnancy can lead to miscarriage or other complications later in pregnancy.

The Early Pregnancy Observational Study

For several years researchers have been asking women to take part in The Early Pregnancy Observational Study (EPOS) which follows women from early pregnancy, right up to birth.

This form of study allows researchers to collect a vast amount of data about women’s clinical history and the outcome of their pregnancy. Evidence collected includes taking blood samples, urine and vaginal tests, and over 1,500 women have been included with ongoing work still happening.

Clinically Vulnerable in Pregnancy

At the beginning of the COVID pandemic, pregnant women were classified into an ‘at risk’ group as they were clinically vulnerable and therefore were advised to shield. However, the true effects of COVID during pregnancy are unclear and there is some emerging evidence that suggests that pregnant women are actually at no greater risk of becoming seriously unwell than other healthy adults.


The information gathered from the EPOS work is now being used to find out more about the effects of COVID during pregnancy. The samples taken will now also be checked for COVID antibodies and biological markers associated with the COVID infection. The research will observe the final pregnancy outcomes to assess whether contracting a COVID infection during pregnancy is linked to early or late pregnancy complications such as gestational diabetes, pre-eclampsia, sow growth, premature birth, or miscarriage.

Get In Touch

If you are concerned about the impact of COVID on your pregnancy, we are here to support and reassure you. We understand that it can be a very worrying time, particularly if you have been experiencing fertility difficulties or miscarriages previous to conceiving. We offer reassurance scans at any point from six weeks. Our expert consultants can offer valuable information about how your pregnancy is progressing, provide peace of mind as well as clear guidance on your pregnancy date.

We also offer a Recurrent Miscarriage Service which involves a comprehensive appointment with one of our expert consultant gynaecologists. Get in touch today to book an appointment to begin investigations into the possible causes.