The COVID vaccine is in full swing within the UK and it is now being offered to everyone over the age of 16. But there have been some concerns raised by pregnant women.
To address these concerns, the Government is introducing a new £7.5 million Preg-CoV clinical trial. This trial focuses on the immunity response of women during pregnancy to vaccination at varying dose intervals.
COVID in Pregnancy
The concerns of pregnant women largely stem from a concern that pregnant women were not included in the initial COVID vaccine trials. However, extensive real-world data now shows that vaccines are both safe and highly effective for pregnant women.
It is important to note that research suggests pregnant women are more likely to become seriously ill from COVID. But following an influx of hospital admissions of unvaccinated pregnant women with COVID, recent research revealed that in fact 98% of pregnant women that were admitted to hospital with COVID had not been vaccinated.
Preg-CoV Clinical Trial
Following a successful vaccination programme including pregnant women in the USA, a clinical trial named Preg-CoV has now been launched in the UK. This looks at the immune response to vaccination at different dose intervals – either 4 to 6 weeks or 8 to 12 weeks.
This data will determine the best timings for vaccines in order to give optimal protection to pregnant mothers and their babies. Furthermore, it will reduce current gaps in knowledge and inform policy recommendations for future vaccination programmes in pregnancy.
The trial includes over 600 pregnant women who will be vaccinated using either the Pfizer/BioNTech or the Moderna vaccine. These women will then be closely monitored throughout their pregnancy and post-birth. It focuses on women who are between 18 and 44 years old, with no pre-existing health conditions.
The women will be given 2 doses of the vaccine at either 4 – 6 weeks or 8 – 12 weeks. Throughout the trial, the pregnant women will regularly have their blood analysed. This will be to gather information on their immune response and how the vaccines are offering protection.
The results from this study are expected to be published towards the end of 2021. If you still have concerns about the COVID vaccination and your pregnancy, book a consultation with our consultants at SureScan.